SELM antibody

Catalog No. ABIN7118863

This Rabbit Polyclonal antibody specifically detects SELM in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for SELM antibody (ABIN7118863)

Target: SELM (Selenoprotein M (SELM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SELM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SELM Antibody

Purpose: SELENOM antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Selenoprotein M

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SELM

Target: SELM (Selenoprotein M (SELM))

Alternative Name: SELENOM

Background:

Synonyms: Selenoprotein M (SelM)|SELENOM|SELM

Background: The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.

Molecular Weight: 16 kDa

Gene ID: 140606

UniProt: Q8WWX9